Publications: Bibliography

Articles

Abstracts and presentations

Articles

Adam Feldman, Michel Assad, Mark B. Davies, Jitendra Mangwani, Enrique Alabort, Mac Tuncer. Cortico-cancellous osseointegration into additively manufactured titanium implants using a load-bearing femoral ovine model. Frontiers in Bioengineering and Biotechnology – Biomaterials (2024) 12:1371693: 1-10.

Maureen T. O’Brien, JoAnn C. L. Schuh, Lyn M. Wancket, Sarah D. Cramer, Kathleen A. Funk, Nicolette D. Jackson, Kamala Kannan, Kevin Keane, Abraham Nyska, Serge D. Rousselle, Adrienne Schucker, Valerie S. Thomas, Stefan Tunev. Scientific and Regulatory Policy Committee Points to Consider for Medical Device Implant Site Evaluation in Nonclinical Studies. Toxicologic Pathology Journal (2022) 50(4): 512-530.

Patrick Rider, Željka Perić Kačarević, Akiva Elad, Daniel Rothamel, Gerrit Sauer, Fabien Bornert, Peter Windisch, Dávid Hangyási, Balint Molnar, Bernhard Hesse, Michel Assad and Frank Witte. Biodegradation of a magnesium alloy fixation screw used in a guided bone regeneration model in beagle dogs. Materials (2022) 15: 4111.

Željka Perić Kačarević, Patrick Rider, Akiva Elad, Drazen Tadic, Daniel Rothamel, Gerrit Sauer, Fabien Bornert, Peter Windisch, Dávid Botond Hangyási, Balint Molnar, Till Kammerer, Bernhard Hesse, Emely Bortel, Marco Bartosch, Frank Witte. Biodegradable magnesium fixation screw for barrier membranes used in guided bone regeneration. Bioactive Materials (2022) 14: 15-30.

Patrick Rider, Željka Perić Kačarević, Akiva Elad, Drazen Tadic, Daniel Rothamel, Gerrit Sauer, Fabien Bornert, Peter Windisch, Dávid Botond Hangyási, Balint Molnar, Emely Bortel, Bernhard Hesse, Frank Witte. Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery. Bioactive Materials (2022) 14: 152-168.

Rym El Khoury, Ivan Tzvetanov, Edward A. Estrada, Edward McCarroll, Eugene Michal, Jack Blumeyer, Louis-Georges Guy, Martin Laflamme and Lewis B. Schwartz. Intravascular treatment of long segments of experimental peripheral arteries with multiple, serial, balloon-expandable, resorbable scaffolds animal model of human peripheral arterial bending and deformation. JVS Vascular Science (2022) 3: 205-210.

Bala Subramanya Pavan Kumar Kandala, Guangqi Zhang, Capucine LCorriveau, Mark Paquin, Madeleine Chagnon, Dana Begun, Vesselin Shanov. Preliminary study on modelling, fabrication by photo-chemical etching and in vivo testing of biodegradable magnesium AZ31 stents. Bioactive Materials (2021) 6(6): 1663-1675.

Michel Assad, Anne Marie Downey, Caroline Cluzel, Yannick Trudel, Nancy Doyle, Simon Authier. Characterization of an acute rodent osteomyelitis infectious model using a tibial intramedullary implant inoculation. Frontiers in Bioengineering and Biotechnology – Biomaterials (2020) 8:567647: 1-10

Eric Strauss, David NM Caborn, John Nyland, Sonida Horng, Madeleine Chagnon, David Wilke. Tissue healing following segmental meniscal allograft transplantation: a pilot study. Knee Surg Sports Traumatol Arthrosc (2019) 27(6): 1931-1938.

Rym El Khoury, Alexander Nikanorov, Edward McCarroll, Guy Leclerc, Louis-Georges Guy, Martin Laflamme, Audrey Mailloux, Lew Schwartz. An animal model of human peripheral arterial bending and deformation. Journal of Surgical Research (2019) 241: 240-246.

Laetitia Keller, Luc Pijnenburg, Ysia Idoux-Gillet, Fabien Bornert, Maryam Tabrizian, Pierrick Auvray, Philippe Rosset, Rosa María Gonzalo-Daganzo, Enrique Gómez Barrena, Luca Gentile, Nadia Benkirane-Jessel. Preclinical safety study of a combined therapeutic bone wound dressing for osteoarticular regeneration. Nature Communications (2019) 10(1): 2156.

Cristiano Susin, Amanda Finger Stadler, Marta L. Musskopf, Mariana de Sousa Rabelo, Umberto D. Ramos, Tiago Fiorini. Safety and efficacy of a novel, gradually anodized dental implant surface: A study in Yucatan mini pigs. Clin Implant Dent Relat Res (2019) 21: 44-54.

Nicolette Jackson, Michel Assad, Derick Vollmer, James Stanley, Madeleine Chagnon. Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-Art in Animal Models, Imaging, and Histomorphometry Techniques. Toxicologic Pathology Journal (2019) 47(3): 280-296.

Madeleine Chagnon, Louis-Georges Guy, Nicolette Jackson. Evaluation of Magnesium-based Medical Devices in Preclinical Studies: Challenges and Points to Consider. Toxicologic Pathology Journal (2019) 47(3): 390-400.

Serge D. Rousselle, Yuval Ramot, Abraham Nyska, Nicolette D. Jackson. Pathology of Bioabsorbable Implants in Preclinical Studies. Toxicologic Pathology Journal (2019). Toxicologic Pathology Journal (2019) 47(3): 358-378.

Michel Assad and Nicolette Jackson. Biocompatibility evaluation of orthopedic biomaterials and medical devices: A review of safety and efficacy models. In: Roger Narayan (Ed.), Elsevier, Encyclopedia of Biomedical Engineering, Vol. 2, pp. 281–309 (2019).

Michael Joner, Philipp Ruppelt, Philine Zumstein, Capucine Lapointe-Corriveau, Guy Leclerc, Anna Bulin, Maria Isabel Castellanos, Eric Wittchow, Michael Haude, Ron Waksman. Preclinical evaluation of degradation kinetics and elemental mapping of first- and second-generation bioresorbable magnesium scaffolds. EuroIntervention 2018;14:e1040-e1048.

Benoît Schaller, John Patrik Matthias Burkhard, Madeleine Chagnon, Stefan Beck, Thomas Imwinkelried, Michel Assad. Fracture healing and bone remodeling with human standard-sized magnesium versus polylactide-co-glycolide (PLGA) plate and screw systems using a mini-swine craniomaxillofacial osteotomy fixation model. Journal of Oral and Maxillofacial Surgery (2018) 76(10): 2138-2150.

Chi-Hung Huang, Sheng-Yang Lee, Sonida Horng, Louis-Georges Guy, Ting-Bin Yu. In vitro and in vivo degradation of microfiber bioresorbable coronary scaffold. Journal of Biomedical Materials Research: Applied Biomaterials (2018) 106B(5): 1842-1850.

Krzysztof Milewski, Roland Fiszer, Piotr P. Buszman, Przemysław Węglarz, Adam Janas, Agata Krauze, Michał Jelonek, Piotr Hirnle, Grzegorz Smolka, Robert Gil, Jacek Białkowski, Paweł E. Buszman. Temporal healing patterns and coverage dynamics after new Polish transcatheter PFO occluder implantation in a swine. Kardiologia Polska (2017) 75(9): 907-913.

Kathleen O’Connell, Caitlin Pierlot, Helen O’Shea, Diane Beaudry, Madeleine Chagnon, Michel Assad, Daniel Boyd. Host Responses to a Strontium Releasing High Boron Glass using a Rabbit Bilateral Femoral Defect Model. Journal of Biomedical Materials Research: Applied Biomaterials (2017) 105B(7): 1818-1827.

Eric Wittchow, Sonja Hartwig. Still room for improvement: Preclinical and bench testing of a thin-strut cobalt-chromium bare-metal stent with passive coating. Journal of Biomedical Materials Research: Applied Biomaterials Part B (2017) 105B(6): 1612-1621.

Waksman R, Zumstein P, Pritsch M, Wittchow E, Haude M, Lapointe-Corriveau C, Leclerc G, Joner M. Second-generation magnesium scaffold Magmaris: device design and preclinical evaluation in a porcine coronary artery model. EuroIntervention. (2017) 13(4):440-449.

Joseph Khoury, Melissa Maxwell, Raymond E. Cherian, James Bachand, Art Kurz, Michael Walsh, Michel Assad, Richard Svrluga. Enhanced Bioactivity and Osseointegration of PEEK with Accelerated Neutral Atom Beam Technology. Journal of Biomedical Materials Research: Applied Biomaterials (2017) 105B(3): 531-543.

Caitlin Pierlot, Lauren Kiri, Kathleen MacDonald, Brett Dickey, Esther Valliant, Madeleine Chagnon, Michel Assad, Mark Filiaggi, Daniel Boyd. A Pilot Evaluation of an Aluminum Free Glass Ionomer Cement using a Sub-Chronic Osseous Defect Model in New Zealand White Rabbits. Materials Letters (2016) 184: 301-304.

Stacy A. Hutchens, Charlie Campion, Michel Assad, Madeleine Chagnon, Karin A. Hing. Efficacy of silicate-substituted calcium phosphate with enhanced strut porosity as a standalone bone graft substitute and autograft extender in an ovine distal femoral critical defect model. Journal of Materials Science: Materials in Medicine (2016) 27(1): 20.

Sharon Kehoe, Salma Amensag, Mark Looney, Robert J. Abraham, and Daniel Boyd “Imageable” Zinc-Silicate Glass Microspheres For Transarterial Embolization: A Renal Artery Embolization Study. Biomed. Glasses (2015) 1:70–79.

Adam Janas, Krzysztof Milewski, Piotr P. Buszman, Przemysław Nowakowski, Michał Jelonek, Bartłomiej Orlik, Agata Krauze, Stefan Samborski, Diane Beaudry, Guy LeClerc, Marek Król, Jean−Martin Lapointe, Wojciech Wojakowski, Anna Turek, Radosław S. Kiesz, Paweł E. Buszman. Safety and biocompatibility of a novel self-expanding nitinol carotid stent with hybrid cell design in a porcine model of neointimal hyperplasia. Kardiologia Polska (2015) 73(4): 240-245.

Roya Zarpak, Oscar David Sanchez, Michael Joner, Louis-Georges Guy, Guy Leclerc and Renu Virmani. A Novel « Pro-healing » Approach: the COMBO™ Dual Therapy Stent from a Pathological View. Minerva Cardioangiologica (2015) 63:31-43.

Lauren Klinker, Stephen Lee, John Worka, John Wright, Yinji Ma, Leon Ptaszeke, Richard C. Webbf, Cliff Liua, Nirav Shetha, Moussa Mansour, John A. Rogers, Yonggang Huang, Hang Chenb, Roozbeh Ghaffari. Balloon catheters with integrated stretchable electronics for electrical stimulation, ablation and blood flow monitoring. Extreme Mechanics Letters (2015) 3:45–54.

Eric Durand, Tahmer Sharkawi, Guy Leclerc, Marine Raveleau, Michael van der Leest, Michel Vert, Antoine Lafont. Head-to-Head Comparison of a Drug-Free Early Programmed Dismantling Polylactic Acid Bioresorbable Scaffold and a Metallic Stent in the Porcine Coronary Artery. Circulation: Cardiovascular Intervention (2014) 7:70-79.

Pil-Ryung Cha, Hyung-Seop Han, Gui-Fu Yang, Yu-Chan Kim, Ki-Ha Hong, Seung-Cheol Lee, Jae-Young Jung, Jae-Pyeong Ahn, Young-Yul Kim, Sung-Youn Cho, Ji Young Byun, Kang-Sik Lee, Seok-Jo Yang, Hyun-Kwang Seok. Biodegradability engineering of biodegradable Mg alloys: Tailoring the electrochemical properties and microstructure of constituent phases. Scientific Reports (2013) 3:2367.

Eric Wittchow, Nina Adden, Johannes Riedmüller, Claudine Savard, Marlen Braune. Bioresorbable drug-eluting magnesium-alloy scaffold: design and feasibility in a porcine coronary model. EuroIntervention (2013) 8(12): 1441-1450.

Sung Youn Cho, Soo-Won Chae, Kui Won Choi, Hyun Kwang Seok, Yu Chan Kim, Jae Young Jung, Seok-Jo Yang, Gyeong Je Kwon, Jong Tack Kim, Michel Assad. Biocompatibility and strength retention of biodegradable Mg-Ca-Zn alloy bone implants. Journal of Biomedical Materials Research: Applied Biomaterials (2013) 101B(2): 201–212.

Michael Joner, Peter W. Radke, Robert A. Byrne, Sonja Hartwig, Kristin Steigerwald, Guy Leclerc, Eric Wittchow. Preclinical evaluation of a novel drug-eluting balloon in an animal model of in-stent stenosis. Journal of Biomaterial Applications (2013) 27(6): 717-726

Krzysztof Milewski, Bogdan Gorycki, Piotr P. Buszman, Michał Jelonek, Diane Beaudry, Jean−Martin Lapointe, Louis−Georges Guy, Motaz Abusamra, Jacek Pająk, Wojciech Kinasz, Wojciech Wojakowski, Guy Leclerc, Robert J. Gil, Paweł E. Buszman. Vascular response and mechanical integrity of the new biodegradable polymer coated sirolimus-eluting PROLIM stent implanted in porcine coronary arteries. Kardiologia Polska (2012) 70(7): 703-711.

Sung Youn Cho, Soo-Won Chae, Kui Won Choi, Hyun Kwang Seok, Hyung Seop Han, Seok-Jo Yang, Young Yul Kim, Jong Tack Kim, Jae Young Jung, Michel Assad. Load-bearing capacity and biological allowable limit of biodegradable metal based on degradation rate in vivo. Journal of Biomedical Materials Research: Applied Biomaterials (2012) 100B(6): 1535-1544

Alexander Sheehy, Steve Hsu, Julie Tai, Don Steinfeld, Amelie Bouchard, Pablo Lema, Claudine Savard, Igor Polyakov, Louis-Georges Guy. Comparative Effects of Paclitaxel and Everolimus Eluting Stents on Coronary Arterial Response in a Porcine Model of Diabetes. Cardiovascular Diabetology (2012) 11: 75

Michael Joner, Robert A. Byrne, Jean-Martin Lapointe, Peter W. Radke, Gerd Bayer, Kristin Steigerwald, Eric Wittchow. Comparative assessment of drug-eluting balloons in an advanced porcine model of coronary restenosis. Thrombosis and Haemostasis (2011) 105: 864-872.

Peter W. Radke, Michael Joner, Alexander Joost, Robert A. Byrne, Sonja Hartwig, Gerd Bayer, Kristin Steigerwald, Eric Wittchow. Vascular effects of paclitaxel following drug-eluting balloon angioplasty in a porcine coronary model: the importance of excipients. EuroIntervention (2011) 7(6): 730-737.

Abstracts and presentations

Andrew K. Wong, Nicolette D. Jackson, Michael Tanzer, Michel Assad, Chau G. Ngo, Brinda Badwe, Lewis Mullen. Local Tissue Response and Bone Ingrowth into Titanium Nitride-Coated 3D-Printed Porous Titanium Structures in a Canine Model. Poster presentation at the 72nd Annual Meeting of the Orthopaedic Research Society, Charlotte, NC, USA, March 27-31, 2026.
Adam J. Griebel, Jeremy E. Schaffer, Bernadette Biong, Fabian Soza, Maria Bates, Michel Assad. Safety and Performance of an Absorbable Nutrient Metal Magnesium Alloy: A Pilot Study using an Ovine Tibial Bicortical Insertion Model. 71th Annual Meeting of the Orthopaedic Research Society, Phoenix, AZ, USA, February 7-11, 2025.
Rym El Khoury, Ivan Tzvetanov, Edward A. Estrada, Edward McCarroll, Louis-Georges Guy, Martin Laflamme and Lewis B. Schwartz. Paclitaxel-eluting, balloon-expandable, bioresorbable vascular scaffolds reduce neointimal thickness and stenosis in an animal model of percutaneous peripheral intervention. Webinar, 2nd Annual Innovation in Vascular Surgery and Endovascular Therapies Award webinar Friday, May 27, 2022 & Oral presentation at VEITH Symposium, New York USA, November 15-19, 2022.

Amy Kent, Spencer Barnes, Mac Tuncer, Catherine Gross, Michel Assad, Mark B. Davies, Jitendra Mangwani, Enrique Alabort. Cortico-Cancellous Osseointegration into Additively Manufactured Titanium Implants using a Load-Bearing Femoral Ovine Model. 68th Annual Meeting of the Orthopaedic Research Society, Tampa, FL, USA, February 4-8, 2022.

Michel Assad, Diane Beaudry, Britta Knight, Yannick Trudel, Annie Reza. Bone Ingrowth Performance Evaluation of a Novel Additive Manufactured Porous Titanium Interbody Spinal Fusion Cage using an Ovine Model. Poster presentation at the 67th Annual Meeting of the Orthopaedic Research Society, All Access, February 12-16, 2021.
Michel Assad, Anne-Marie Downey, Caroline Cluzel, Yannick Trudel, Nancy Doyle, Simon Authier. Optimization of an Infectious Rodent Osteomyelitis Model using an Inoculated Intramedullary Tibial Implant. Poster presentation at the 11th World Biomaterials Congress, WBC 2020 Virtual, December 11-15, 2020.
Michel Assad, Laetitia Keller, Gilles Claeys, Yannick Trudel, Nadia Benkirane-Jessel. Poly-ε-Caprolactone Nanofibrous Wound Dressing for Autologous Cell Therapy: A Safety and Performance Evaluation using an Ovine Intraarticular Regeneration Model. Poster presentation at the 11th World Biomaterials Congress, WBC 2020 Virtual, December 11-15, 2020.

Louis-Georges Guy, Rosa Kaviani, Martin Laflamme, Nial Bullett, Naveed Ahmed, Kadem Al-Lamee, Yoshinobu Onuma. Evaluation of ArterioSorb™, a PDLA and Sirolimus Coated PLLA Bioresorbable Scaffold, in Swine Model over 6 Months. Poster presentation at the 11th World Biomaterials Congress, Glasgow, Scotland, December 11-16, 2020.

Maureen O’Brien, Richard Mowry. Slide Thickness Can Affect Assessment of Subcutaneous Medical Device Biocompatibility. Poster presentation at the 11th World Biomaterials Congress, Glasgow, Scotland, December 11-16, 2020.
Louis-Georges Guy. Preclinical evaluation of drug device combination products: particularities and challenges. Invited speaker at the Pharmaceutical & BioScience Society – San Francisco Bay (PBSS) symposium Drug/Device Combinations, Foster City, CA, USA, February 11, 2020.
Michel Assad, Sandra Iacampo, Madeleine Chagnon, Yannick Trudel, Shilesh Jani, Brody Nelson, Stan Despres. Porous Asymmetrical Beaded Coating Bone Ingrowth Evaluation using an Ovine Bilateral Long-Bone Model. Poster presentation at the 66th Annual Meeting of the Orthopaedic Research Society, Phoenix, AZ, USA, February 8-11, 2020.
Luis Fernando Negro Silva, Julius Haruna, Pritpal Malhi, Simon Authier, Yannick Trudel, Raluca Kubaszky, Victoria Badalone, Michel Assad and Louis-Georges Guy. Bilateral Distal Femoral Epiphyseal Defect Models for Safety Testing: A 5-Week Rat Bone Healing Study. Oral presentation at the 58th Annual Meeting of the Society of Toxicology and ToxExpo, Baltimore, MD, USA, March 14, 2019. Abstract published in The Toxicologist (2019) 168, (1) 517.
Louis-Georges Guy, Martin Laflamme, Fabian Soza, Guy Leclerc. Functional and safety evaluation of bioresorbable scaffold in swine coronary arteries. Poster presentation at the 58th Annual Meeting of the Society of Toxicology and ToxExpo, Baltimore, MD, USA, March 10-14, 2019. Abstract published in The Toxicologist (2019) 168, (1) 251.
Louis-Georges Guy, Michel Assad, Nicolette Jackson, Madeleine Chagnon, Fabian Soza, Guy Leclerc. Correlation of micro-CT imaging with histology sections, an important tool to understand the structural function and biological response to implantable medical devices. Poster presentation at the 58th Annual Meeting of the Society of Toxicology and ToxExpo, Baltimore, MD, USA, March 10-14, 2019. Abstract published in The Toxicologist (2019) 168, (1) 435.
Lew Schwartz, Rym El Khoury, Alex Nikanorov, Edward McCarroll, Louis-Georges Guy, Martin Laflamme, Guy Leclerc, Audrey Mailloux, Christopher Haigm, Ivan Tzvetanov, Alex Estrada. An animal model of human peripheral arterial bending and deformation. Oral presentation at the 14th Annual Academic Surgical Congress, Houston, TX, USA, February 5-7, 2019.
Michel Assad, Bryan J. McEntire, Sandra Iacampo, Yannick Trudel, B. Sonny Bal. Osseointegration and Biocompatibility Evaluation of Silicon Nitride Composite Using Ovine Distal Femoral Epiphyseal Insertion and Rabbit Paravertebral Muscle Implantation Models. Poster presentation at the 65th Annual Meeting of the Orthopaedic Research Society, Austin, TX, USA, February 2-5, 2019.
Michel Assad, Madeleine Chagnon, Nicolette Jackson. Biocompatibility evaluation of new orthopedic devices for regulatory testing. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Madeleine Chagnon, Nicolette Jackson, Michel Assad. Pre-clinical evaluation of explanted orthopedic biomaterials: histology challenges and troubleshooting. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Michel Assad, Yannick Trudel, Madeleine Chagnon, Nicolette Jackson, Bertrand Lussier. The state-of-the-art animal models for orthopedic implant performance testing. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Michel Assad, Fabian Soza, Nicolette Jackson, Louis-Georges Guy. Micro-computed tomography for qualitative and quantitative evaluation of explanted orthopedic medical devices. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Nicolette Jackson, Madeleine Chagnon, Michel Assad. A review of current histopathology evaluation systems for orthopedic biomaterials. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Syamend Saeed, Michel Assad, Akiva Elad, Romina Amberg, Anzelika Schreiber, Sarah Heilmann, Tim Fienitz, Daniel Rothamel, Frank Witte. Open-porous scaffolds made of short magnesium fibers as bone defect fillers. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Michel Assad, Bryan J. McEntire, Sandra Iacampo, Madeleine Chagnon, Yannick Trudel, B. Sonny Bal. Osteoinduction and osseointegration evaluation of Si3N4 implants using rabbit ectopic bone formation and ovine bilateral long-bone insertion models. Poster presentation at the 39th SICOT Orthopaedic World Congress, Montréal, QC, Canada, October 10-13, 2018.
Luis Fernando Negro Silva, Julius Haruna, Pritpal Malhi, Simon Authier, Yannick Trudel, Raluca Kubaszky, Michel Assad. Bilateral Distal Femoral Epiphyseal Defect Models for Safety Testing: A 5-Week Rat Bone Healing Study. Poster presentation at the Annual Meeting of the American Society for Bone and Mineral Research, Montréal, QC, Canada, September 28-October 1, 2018.
Louis-Georges Guy. Preclinical evaluation of bioabsorbable scaffolds in minipig vasculature: imaging technologies to evaluate device performance, safety profile and structural integrity of the implant. Oral presentation at the 12th Minipig Research Forum, Barcelona, Spain, May 16-18, 2018.
Michel Assad, Benoît Schaller, John Patrik Matthias Burkhard, Madeleine Chagnon, Stefan Beck, Thomas Imwinkelried, Louis-Georges Guy, Guy Leclerc. Use of miniswine to evaluate magnesium-based maxillofacial plates and screws. Poster presentation at the 12th Minipig Research Forum, Barcelona, Spain, May 16-18, 2018.
Joseph Khoury, Eric J. Woodard, Gilles Claeys, Michel Assad. Novel Accelerated Neutral Atom Beam Processing as a PEEK Surface Treatment: A Four-Month Preliminary Study using an Ovine Lumbar Intervertebral Spinal Fusion Model. Poster presentation at the 64th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, March 10-13, 2018.
Michel Assad, Diane Beaudry, Antoinette Forcione, Madeleine Chagnon, Fabian Sosa, Robin Turcotte, Mathieu Beaudoin, Yannick Trudel, Bertrand Lussier. Evaluation of Bone Substitutes using a Rabbit Posterolateral Lumbar Intertransverse Process Spinal Fusion (PLF) Model: A Subchronic Pilot Study. Poster presentation at the Annual Meeting of the Society for Biomaterials, Minneapolis, MN, USA, April 4-8, 2017.
Robert A. Poggie, Louis-Philippe Lefebvre, Stéphanie Grenier, Madeleine Chagnon, Michel Assad. Efficacy of a new porous titanium compression screw using an ovine osseointegration model. Poster presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Benoit Schaller, Michel Assad, Stefan Beck, Thomas Imwinkelried, Tateyuki Iizuka. Comparison of magnesium versus polylactide-co-glycolide resorbable plates and screws using a new porcine maxillofacial fracture fixation model, a pilot study. Oral presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Sonida Horng, Louis-Georges Guy, Martin Laflamme, Claudine Savard, Nagarajan Ramesh, Howard Huang, Anuja Patel, John Yan, Guy Leclerc, Vinayak Bhat. Evaluation of DESolve, a Drug Eluting Bioresorbable Scaffold in a Porcine Coronary Artery Model. Poster presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Michel Assad, Madeleine Chagnon, Kelly Richelsoph, Robert Crews, Marc Richelsoph. Biocompatibility of a novel expandable threaded screw using an ovine bilateral femoral model: a preliminary study. Poster presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Madeleine Chagnon, Claudine Savard. Challenges in post-mortem preparation of orthopedic implanted devices. Poster presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Chi-Hung Huang, Louis-Georges Guy, Sonida Horng, Fabian Soza, Guy LeClerc, Ting-Bin Yu, Solomon Su. Fast degradation but low fracture property of Mirage Microfiber Bioresorbable Scaffold using a swine internal thoracic artery model: a preliminary study. Poster presentation at the 10th World Biomaterials Congress, Montréal, QC, Canada, May 17-22, 2016.
Louis-Georges Guy. Biodegradable metals evaluation in animal experiments. Keynote lecture at the 8th Symposium on Biodegradable Metals, Montréal, QC, Canada, May 14-17, 2016.
Louis-Georges Guy, Fabian Soza, Capucine Lapointe-Corriveau, Guy LeClerc. Qualitative evaluation of magnesium implants integrity with micro-CT (Computed Tomography) and quantitative degradation evaluation. Poster presentation at the 8th Symposium on Biodegradable Metals, Montréal, QC, Canada, May 14-17, 2016.
Benoit Schaller, Michel Assad, Stefan Beck, Thomas Imwinkelried, Tateyuki Iizuka. Performance of a magnesium plate/screws system in a miniature pig midface and mandibular fracture fixation model. Oral presentation at the 8th Symposium on Biodegradable Metals, Montréal, QC, Canada, May 14-17, 2016.
Jeannot Potvin, Dongming Hou, Elena Ladich, Barbara Huibregtse, Renu Virmani, Keith Dawkins, Amelie Bouchard, Guy LeClerc. Hemodynamic and Biology Response of A Full Repositionable and Retrievable TAVI System in a Sheep Model. Poster presentation at CIT (China Interventional Therapeutics), Beijing, China, March 17-20, 2016.
Robert A. Poggie, Louis-Philippe Lefebvre, Stéphanie Grenier, Madeleine Chagnon, Michel Assad. Osseointegration and Defect Repair with a New Porous Titanium Screw in Ovine Long-Bone Models for Gap-Healing, Osteonecrosis, and Bone Ingrowth. Oral presentation at the 62nd Annual Meeting of the Orthopaedic Research Society, Orlando, FL, USA, March 5-8, 2016.
K.D. Brewer, C. Davis, X.F. Zhang, J. Fraser, F. Heelan, E. Tonkopi, P. Casey, C. Brown, S. Kehoe, D. Boyd, R. Abraham. Multimodal Imaging of Novel Embolic Microspheres for Transarterial Embolization in New Zealand White Rabbits. World Molecular Imaging Congress (WMIC) 2016, New York City, NY, September 7-10, 2016.
S. Kehoe, S. Amensag, X.F. Zhang, S.C. Goodwin, R.J. Lewandowski, D. Liu, D. Boyd, R.J. Abraham. A Bilateral Partial Swine Renal Artery Embolization Study using “Imageable” Embolic Microspheres: Assessment of Mechanism of Occlusion, Embolization Effectiveness, Device Migration and Safety. Society of Interventional Radiology (SIR) 2016 Annual Meeting, Vancouver, BC, April 2-7, 2016.
Guy Leclerc, Diane Beaudry, Louis-Georges Guy, Matt Palin. Preclinical Fracture Analysis of Bioabsorbable Scaffolds. Poster presentation at the CRT-16, Washington, DC, USA, February 20-23, 2016. Abstract published in JACC: Cardiovascular Interventions. 2016; 9: Suppl S, S55.
Roger Kessels, Amelie Bouchard, Louis-Georges Guy, Guy LeClerc, H. Ibrahim Korkmaz, Hans W. Niessen, Gregg W. Stone. Early PICSO preserves LVEF in porcine acute myocardial infarction. Oral presentation at TCT, November 2015. Abstract published in Journal of the American College of Cardiology. 2015; 66: B4.
Madeleine Chagnon. Preparation and Analysis of Orthopedic Implanted Devices. Oral presentation at the Combined Annual Meeting of the American College of Veterinary Pathologists, American Society for Veterinary Clinical Pathology, and Society of Toxicologic Pathology, Minneapolis, MN, USA, October 17-21, 2015.
Michel Assad, Diane Beaudry, Joanne Wilson, Bertrand Lussier, Madeleine Chagnon, Elizabeth Pluhar, Matthew Cantwell. Safety and Efficacy of PEEK Intramedullary Nail Fixation System using an Ovine Tibial Fracture Repair Model. Oral presentation at the Annual Meeting of the Society for Biomaterials, Charlotte, NC, USA, April 15-18, 2015.
Joseph Khoury, Cathy Tkaczyk, Art Kurz, James Bachand, Richard C. Svrluga, Michel Assad. Accelerated Neutral Atom Beam Processing Improves PEEK In Vivo Osseointegration. Oral presentation at the 61st Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, USA, March 28-31, 2015.
S. Kehoe, R.J. Abraham, D. Boyd. Unilateral renal artery embolization in yucutan miniswine with imageable embolic microspheres. Society of Interventional Radiology, Atlanta, GA, February 28th – March 5th, 2015. Published in a supplement of the Journal of Vascular Interventional Radiology, 26(2), S79-80, doi.org/10.1016/j.jvir.2014.12.221.
Guy Leclerc. Novel Interventional Technologies – TAVR and CHF. Oral presentation at the Meril Symposium during TCT 2014, Washington, DC USA, September 14, 2014.
Stacy Hutchens, Charlie Campion, Michel Assad, Cathy Tkaczyk, Karin Hing. Efficacy of silicate-substituted calcium phosphate with increased strut porosity as a standalone bone graft substitute and graft extender in an ovine critical defect model. Poster presentation at the 22nd Annual Meeting of the European Orthopaedic Research Society, Nantes, France, July 2-4, 2014.
Cathy Tkaczyk, Thomas Imwinkelried, Michel Assad, Benoit Schaller, Tateyuki Iizuka, Stefan Beck. Efficacy evaluation of resorbable magnesium plates and screws using a miniswine maxillofacial fracture repair model. Oral presentation at the 22nd Annual Meeting of the European Orthopaedic Research Society, Nantes, France, July 2-4, 2014.
Jeannot Potvin, Renu Virmani, Elena Ladich, Dongming Hou, Crystal Anderson-Cunanan, Barbara A Huibregtse, Keith D Dawkins, Guy LeClerc. Hemodynamic evaluation of a fully repositionable TAVI system in a novel chronic ovine model of transfemoral orthotopic aortic valve implants. Poster presented at EuroPCR, Paris, France, May 20-23, 2014.
Elena Ladich, Barbara Huibregtse, Keith Dawkins, Guy Leclerc, Dongming Hou, Amelie Bouchard, Jeannot Potvin, Renu Virmani. Pathology of explanted aortic valves previously deployed in the orthotopic position in an ovine TAVI model. Poster presented at EuroPCR, Paris, France, May 20-23, 2014.
Jeannot Potvin, Keith D Dawkins, Dominic J Allocco, Amelie Bouchard, Robert Chang, Barbara Huibregtse, Lise Lachance, Guy LeClerc. Transcatheter Orthotopic Aortic Valve Implantation In Sheep: Chronic Survival And Valve Performance Evaluation. Poster presented at TCT in October 2013 (Selected in TCT top 50 poster). Abstract published in Journal of the American College of Cardiology. 2013; 62: B247.
Louis-Georges Guy. Preclinical evaluation of magnesium stent. Oral presentation at EuroPCR in May 2013.
Jason M. Cuellar, Vanessa G. Cuellar, Shawn Browning, Gaetano J. Scuderi, S. Raymond Golish, Lewis S. Hanna. Is there a chondroprotective effect of autologous protease inhibitor concentrate on an osteoarthritis rabbit model? A pilot study. Poster presented at the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, January 26-29, 2013.
Louis-Georges Guy. Cardiovascular and orthopedic magnesium-based bioabsorption devices: Preclinical challenges. Invited speaker at State of the Art in Biodegradable Metals – Think-Tank Workshop at the FDA in March 2012.
Guy Leclerc, Louis-Georges Guy, Jean-Martin Lapointe, Martin Laflamme, Sonida Horng, Vinayak Bhat, Howard Huang, Anuja Patel, John Yan. Pre-clinical Evaluation of a Myolimus-Eluting Bioresorbable Polymeric Scaffold in the Porcine Coronary Artery Model. Poster presented at TCT in November 2011, Abstract published in Journal of the American College of Cardiology 2011; 58: B122.
Louis-Georges Guy, Steven Hsu, Alexander Sheehy, Donald Steinfeld, Amelie Bouchard, Julie Tai, Igor Polyakov, Guy Leclerc. Characterization of Streptozotocin Induced Diabetes and Evaluation of Vascular Response to Current Drug-Eluting Stents in a Swine Model. Oral presentation at AHA in November 2010, Abstract published in Circulation 2010; 122: A16369.
Louis-Georges Guy. Biotronik DREAMS: Drug Eluting Absorbable Metal System Preclinical results and update on clinical trial program. Oral presentation at EuroPCR in May 2010.
G. Sylvester Price, Jean-Martin Lapointe, Diane Beaudry, Louis-Georges Guy, Guy Leclerc, Campbell Rogers. Comparative Vascular Safety Profile of Sirolimus-Eluting Reservoir Technology Stents and Permanent Surface Coated Drug-Eluting Stents in the Porcine Coronary Artery Model at 90 and 180 days. Poster presented at EuroPCR in May 2010.
G. Sylvester Price, Jean-Martin Lapointe, Diane Beaudry, Louis-Georges Guy, James R.L. Stanley, Philip Seifert, Guy Leclerc, Campbell Rogers. Comparative Vascular Safety Profile of Sirolimus-Eluting Reservoir Technology Stents and Coated Drug-Eluting Stents in the Porcine Coronary Artery Model at 30 days. Oral presentation at LDDR in February 2010.
G. Sylvester Price, Jean-Martin Lapointe, Diane Beaudry, Louis-Georges Guy, James R.L. Stanley, Philip Seifert, Guy Leclerc, Campbell Rogers. Comparative Vascular Safety Profile of Sirolimus-Eluting Reservoir Technology Stents and Coated Drug-Eluting Stents in the Porcine Coronary Artery Model. Poster presented at TCT in October 2009, Abstract published in American Journal of Cardiology 2009; 104: 183D.
G. Sylvester Price, Jean-Martin Lapointe, Andrew Luk, Louis-Georges Guy, Gary Steese-Bradley, John Dooley, Campbell Rogers. Vascular Safety of Overlapping Sirolimus-Eluting Reservoir Technology Stents in the Porcine Coronary Artery Model. Poster presented at Innovation in Intervention: i2 Summit in March 2009. Abstract published in Journal of the American College of Cardiology 2009; 53; A74.
Guy Leclerc, Louis-Georges Guy, Jean-Martin Lapointe, Martin Laflamme, Capucine Lapointe-Corriveau, Pierre Helie, Lynn Meredith, John Yan, Irina Astafieva, Vinayak Bhat. Evaluation of the Elixir NovolimusTM Eluting Coronary Stent System with Durable and Bioabsorbable Polymer Coatings in the Porcine Coronary Model. Poster presented at Innovation in Intervention: i2 Summit in March 2009.

Ian Copland, Sandra Iacampo, Louis-Georges Guy, Valerio DiTizio, Guy LeClerc. Assessing Cellular Therapy in Large Animal Models: Feasibility and Efficacy Trials. Poster presented at Phacilitate Cell & Gene Therapy Forum in January 2009.

Guy Leclerc, Louis-Georges Guy, Jean-Martin Lapointe, Martin Laflamme, Capucine Lapointe-Corriveau, Pierre Helie, Lynn Meredith, John Yan, Irina Astafieva, Vinayak Bhat. Pre-clinical Evaluation of the Elixir MyolimusTM Eluting Coronary Stent System with Durable Polymer in the Porcine Coronary Model. Poster presented at TCT in October 2008. Abstract published in American Journal of Cardiology 2008; 102: 161i-162i.
Guy Leclerc, Louis-Georges Guy, Jean-Martin Lapointe, Martin Laflamme, Capucine Lapointe-Corriveau, Pierre Helie, Lynn Meredith, John Yan, Irina Astafieva, Vinayak Bhat. Evaluation of the Elixir NovolimusTM Eluting Coronary Stent System with Durable Polymer coatings in the Porcine Coronary Model. Poster presented at TCT in October 2008. Abstract published in American Journal of Cardiology 2008; 102: 162i-163i.